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Exercise has long been recognized for its dual benefits to both physical and mental health, with scientific research increasingly focusing on the molecular mechanisms behind these effects. While enhanced blood circulation, stress hormone suppression, and endorphin release contribute to the well-documented mental well-being associated with physical activity, recent studies have highlighted the critical role of brain-derived neurotrophic factor (BDNF). This hormone, produced by the brain and peripheral tissues like skeletal muscle, liver, and adipose tissue, supports neuronal growth, survival, and synaptic plasticity, which are essential for learning, memory, and cognitive resilience.
High-intensity exercise, such as sprinting or heavy weightlifting, creates conditions where the body's oxygen supply cannot meet muscular demands, leading to anaerobic glycolysis. This process breaks down glucose and releases lactate, traditionally viewed as a metabolic byproduct. However, emerging evidence suggests lactate may serve as a key signaling molecule that initiates a cascade leading to BDNF expression. Researchers have speculated that lactate accumulation during intense physical exertion could be the starting signal for the physiological chain that promotes brain health, though the exact mechanisms remained unclear until recently.
A groundbreaking study published in Frontiers in Cellular Neuroscience has now demonstrated that artificially elevating blood lactate levels through intravenous infusion can mimic the neurological benefits of exercise. In a randomized crossover study involving 12 healthy volunteers aged 20 to 40, researchers administered one-hour IV infusions of sodium lactate after overnight fasting, with control infusions of saline solution for comparison. Blood samples taken every 10 minutes revealed that lactate infusion achieved blood concentrations characteristic of medium to intense exercise, ultimately boosting levels of pro-BDNF, the precursor to the brain health hormone.
Lead author Dr. Marcus Moberg, a senior lecturer at the Swedish School of Sport and Health Sciences in Stockholm, emphasized the potential clinical applications of these findings. He suggested that high-intensity exercise exposing the brain to elevated lactate levels could be recommended for healthy neurological aging, and that lactate infusion might offer a targeted, individualized approach for populations with compromised brain health. This research not only clarifies how exercise benefits the brain but also opens avenues for non-exercise interventions to replicate these effects, particularly for those unable to engage in intense physical activity.

Oslo police have issued a stark warning to parents about the dangers of encrypted messaging applications on children's phones, stating there is "no reason" for minors to use such services. During a digital parenting meeting streamed online Sunday afternoon, authorities highlighted how platforms including Telegram, Signal, WhatsApp, and Zangi are being exploited by criminal networks to recruit young people for serious offenses.
Section leader Astri Johanne Holm of Oslo East's local police station emphasized that adults have been "too naive" about children's online activities. "Be interested in what your child is doing on social platforms," Holm advised parents. "There's no reason for a child or youth to walk around with an encrypted app on their phone." The warning comes amid growing concerns about criminal groups targeting vulnerable minors through digital channels.
Recent police operations have resulted in multiple arrests of underage individuals across Norway, with cases linked to criminal networks including Sweden's Foxtrot network. Authorities report that children as young as eleven are being recruited for criminal activities. Holm noted that while many people use encrypted apps legally to protect privacy, criminals exploit these platforms to avoid scrutiny from both police and parents.
The digital parenting event attracted significant public interest, with between 5,000 and 10,000 people following the broadcast across Facebook, YouTube, Instagram, and Discord platforms. During the session, parents submitted over 200 questions about monitoring children's online activity without violating their privacy. Police recommended maintaining open dialogue and curiosity about children's apps and interests as the best prevention strategy, while also implementing broader measures including collaboration with child protection services and schools.